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STK16

GENERAL INFORMATION

Gene name

 STK16

Gene description

 Serine/threonine kinase 16

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA029450
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Oral mucosa

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STK16 (HGNC Symbol)

Synonyms

 MPSK, PKL12

Description

 Serine/threonine kinase 16 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 219245455 - 219250337

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115661 (version 83.38)

Entrez gene

 8576

UniProt

 O75716 (UniProt - Evidence at protein level)

neXtProt

 NX_O75716

Antibodypedia

 STK16 antibodies

PROTEIN BROWSER
STK16-001
STK16-003
STK16-004
STK16-007
STK16-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STK16-001
ENSP00000386928
ENST00000409638
O75716 [Direct mapping]
Serine/threonine-protein kinase 16
A0A024R440 [Target identity:100%; Query identity:100%]
Serine/threonine kinase 16, isoform CRA_a
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004715 [non-membrane spanning protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005798 [Golgi-associated vesicle]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006468 [protein phosphorylation]
GO:0016020 [membrane]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046777 [protein autophosphorylation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
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 305 aa
34.7 kDa 		No 0
STK16-003
ENSP00000386309
ENST00000409516
B4DPS1 [Direct mapping]
Serine/threonine-protein kinase 16; cDNA FLJ60771, highly similar to Serine/threonine-protein kinase 16 (EC 2.7.11.1)
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
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 187 aa
20.7 kDa 		No 0
STK16-004
ENSP00000379964
ENST00000396738
O75716 [Direct mapping]
Serine/threonine-protein kinase 16
A0A024R440 [Target identity:100%; Query identity:100%]
Serine/threonine kinase 16, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004715 [non-membrane spanning protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0016020 [membrane]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0046777 [protein autophosphorylation]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 305 aa
34.7 kDa 		No 0
STK16-007
ENSP00000387156
ENST00000409260
B8ZZN3 [Direct mapping]
Serine/threonine-protein kinase 16
Show all
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
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 350 aa
39.5 kDa 		No 0
STK16-012
ENSP00000386553
ENST00000409743
B8ZZI5 [Direct mapping]
Serine/threonine-protein kinase 16
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
Show all
 273 aa
30.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.