Cell atlas - MIIP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MIIP

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	MIIP
Gene description	Migration and invasion inhibitory protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Cell line enriched (HDLM-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA044948
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA044948	A-431	Nucleoplasm
	HPA044948	A-431	Cytosol
	HPA044948	U-2 OS	Nucleoplasm
	HPA044948	U-2 OS	Cytosol
	HPA044948	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	MIIP (HGNC Symbol)
Synonyms	FLJ12438, IIp45
Description	Migration and invasion inhibitory protein (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers. [provided by RefSeq, Sep 2011]
Chromosome	1
Cytoband	p36.22
Chromosome location (bp)	12019466 - 12032045
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116691 (version 83.38)
Entrez gene	60672
UniProt	Q5JXC2 (UniProt - Evidence at protein level)
neXtProt	NX_Q5JXC2
Antibodypedia	MIIP antibodies

PROTEIN BROWSER

MIIP-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MIIP-001 ENSP00000235332 ENST00000235332	Q5JXC2 [Direct mapping] Migration and invasion-inhibitory protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	388 aa 42.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.