Expression of OSCP1 in cancer - Summary - The Human Protein Atlas

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OSCP1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OSCP1
Gene description	Organic solute carrier partner 1
Protein class	Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA028436
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and endometrial cancer (favourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028436

GENE INFORMATION
Gene name	OSCP1 (HGNC Symbol)
Synonyms	C1orf102, NOR1
Description	Organic solute carrier partner 1 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.3
Chromosome location (bp)	36415827 - 36450451
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116885 (version 83.38)
Entrez gene	127700
UniProt	Q8WVF1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WVF1
Antibodypedia	OSCP1 antibodies

PROTEIN BROWSER

OSCP1-002	OSCP1-004	OSCP1-005	OSCP1-006	OSCP1-010	OSCP1-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OSCP1-002 ENSP00000235532 ENST00000235532	Q8WVF1 [Direct mapping] Protein OSCP1 Show all	Transporters Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0009925 [basal plasma membrane] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	379 aa 43.3 kDa	No	0
OSCP1-004 ENSP00000346216 ENST00000354267	Q8WVF1 [Direct mapping] Protein OSCP1 Show all	Transporters Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0009925 [basal plasma membrane] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	223 aa 26.4 kDa	No	0
OSCP1-005 ENSP00000390820 ENST00000433045	C9JF58 [Direct mapping] Protein OSCP1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		334 aa 38.2 kDa	No	0
OSCP1-006 ENSP00000426981 ENST00000468441	H0YAG0 [Direct mapping] Protein OSCP1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.2 kDa	No	0
OSCP1-010 ENSP00000349052 ENST00000356637	Q8WVF1 [Direct mapping] Protein OSCP1 Show all	Transporters Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0009925 [basal plasma membrane] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	389 aa 44.6 kDa	No	0
OSCP1-013 ENSP00000396417 ENST00000445843	H7C0S2 [Direct mapping] Protein OSCP1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		255 aa 29.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.