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SYF2

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GENERAL INFORMATION

Gene name

 SYF2

Gene description

 SYF2 pre-mRNA-splicing factor

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the nuclear speckles.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nuclear speckles (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA070710
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the nuclear speckles.

Main location

 Nuclear speckles (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA070710 SH-SY5Y Nuclear speckles
HPA070710 SK-MEL-30 Nuclear speckles
HPA070710 U-2 OS Nuclear speckles

GENE INFORMATION

Gene name

 SYF2 (HGNC Symbol)

Synonyms

 CBPIN, DKFZp564O2082, fSAP29, NTC31, p29

Description

 SYF2 pre-mRNA-splicing factor (HGNC Symbol)

Entrez gene summary

 This gene encodes a nuclear protein that interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 p36.11

Chromosome location (bp)

 25222679 - 25232502

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000117614 (version 83.38)

Entrez gene

 25949

UniProt

 O95926 (UniProt - Evidence at protein level)

neXtProt

 NX_O95926

Antibodypedia

 SYF2 antibodies

PROTEIN BROWSER
SYF2-001
SYF2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SYF2-001
ENSP00000236273
ENST00000236273
O95926 [Direct mapping]
Pre-mRNA-splicing factor SYF2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0000974 [Prp19 complex]
GO:0001701 [in utero embryonic development]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0007095 [mitotic G2 DNA damage checkpoint]
GO:0007369 [gastrulation]
GO:0008284 [positive regulation of cell proliferation]
GO:0044822 [poly(A) RNA binding]
GO:0048568 [embryonic organ development]
GO:0071010 [prespliceosome]
GO:0071012 [catalytic step 1 spliceosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0071014 [post-mRNA release spliceosomal complex]
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 243 aa
28.7 kDa 		No 0
SYF2-004
ENSP00000346330
ENST00000354361
O95926 [Direct mapping]
Pre-mRNA-splicing factor SYF2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0000974 [Prp19 complex]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0044822 [poly(A) RNA binding]
GO:0071010 [prespliceosome]
GO:0071012 [catalytic step 1 spliceosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0071014 [post-mRNA release spliceosomal complex]
Show all
 201 aa
23.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.