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FKBP15

GENERAL INFORMATION

Gene name

 FKBP15

Gene description

 FK506 binding protein 15, 133kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA007979
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 FKBP15 (HGNC Symbol)

Synonyms

 FKBP133, KIAA0674, PPP1R76, WAFL

Description

 FK506 binding protein 15, 133kDa (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q32

Chromosome location (bp)

 113161006 - 113221361

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119321 (version 83.38)

Entrez gene

 23307

UniProt

 Q5T1M5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5T1M5

Antibodypedia

 FKBP15 antibodies

PROTEIN BROWSER
FKBP15-001
FKBP15-002
FKBP15-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FKBP15-001
ENSP00000416158
ENST00000446284
A0A0A0MT60 [Direct mapping]
Peptidyl-prolyl cis-trans isomerase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000413 [protein peptidyl-prolyl isomerization]
GO:0003755 [peptidyl-prolyl cis-trans isomerase activity]
GO:0006457 [protein folding]
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 1244 aa
136.3 kDa 		No 0
FKBP15-002
ENSP00000415733
ENST00000414250
X6RKW4 [Direct mapping]
Peptidyl-prolyl cis-trans isomerase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000413 [protein peptidyl-prolyl isomerization]
GO:0003755 [peptidyl-prolyl cis-trans isomerase activity]
GO:0006457 [protein folding]
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 497 aa
53 kDa 		No 0
FKBP15-201
ENSP00000238256
ENST00000238256
Q5T1M5 [Direct mapping]
FK506-binding protein 15
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005769 [early endosome]
GO:0005884 [actin filament]
GO:0006457 [protein folding]
GO:0006897 [endocytosis]
GO:0010923 [negative regulation of phosphatase activity]
GO:0016020 [membrane]
GO:0030424 [axon]
GO:0030426 [growth cone]
Show all
 1219 aa
133.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.