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NRDE2

GENERAL INFORMATION

Gene name

 NRDE2

Gene description

 NRDE-2, necessary for RNA interference, domain containing

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues at variable levels.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA047050 , HPA050583
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NRDE2 (HGNC Symbol)

Synonyms

 C14orf102, FLJ14051

Description

 NRDE-2, necessary for RNA interference, domain containing (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q32.11

Chromosome location (bp)

 90267856 - 90332137

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119720 (version 83.38)

Entrez gene

 55051

UniProt

 Q9H7Z3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H7Z3

Antibodypedia

 NRDE2 antibodies

PROTEIN BROWSER
NRDE2-001
NRDE2-007
NRDE2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NRDE2-001
ENSP00000346335
ENST00000354366
Q9H7Z3 [Direct mapping]
Protein NRDE2 homolog
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
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 1164 aa
132.7 kDa 		No 0
NRDE2-007
ENSP00000452071
ENST00000554464
H0YJT0 [Direct mapping]
Protein NRDE2 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 204 aa
23.6 kDa 		No 0
NRDE2-201
ENSP00000486385
ENST00000628832
G3V338 [Direct mapping]
Protein NRDE2 homolog
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
 43 aa
4.7 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.