We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Moderate to strong cytoplasmic staining was observed in several gliomas and a few hepatocellular carcinomas. A few endometrial cancers showed moderate to strong cytoplasmic and nuclear immunoreactivity. Remaining cancers were negative.
GENE INFORMATION
Gene name
CRIPT (HGNC Symbol)
Synonyms
HSPC139
Description
Cysteine-rich PDZ-binding protein (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that binds to the PDZ3 peptide recognition domain. The encoded protein may modulates protein interactions with the cytoskeleton. A mutation in this gene resulted in short stature with microcephaly and distinctive facies. [provided by RefSeq, Jun 2014]