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A few ovarian, endometrial and cervical cancer displayed moderate cytoplasmic positivity. A rare case of malignant carcinoid was strongly stained. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
ADCY7 (HGNC Symbol)
Synonyms
AC7, KIAA0037
Description
Adenylate cyclase 7 (HGNC Symbol)
Entrez gene summary
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]