Fields »
ABOUT
HELP
BLOG
KIF18A

GENERAL INFORMATION

Gene name

 KIF18A

Gene description

 Kinesin family member 18A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA039312 , HPA039484
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Esophagus

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION

Gene name

 KIF18A (HGNC Symbol)

Synonyms

 DKFZP434G2226, PPP1R99

Description

 Kinesin family member 18A (HGNC Symbol)

Entrez gene summary

 KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008]

Chromosome

 11

Cytoband

 p14.1

Chromosome location (bp)

 28020620 - 28108308

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000121621 (version 83.38)

Entrez gene

 81930

UniProt

 Q8NI77 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NI77

Antibodypedia

 KIF18A antibodies

PROTEIN BROWSER
KIF18A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF18A-001
ENSP00000263181
ENST00000263181
Q8NI77 [Direct mapping]
Kinesin-like protein KIF18A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0001726 [ruffle]
GO:0003777 [microtubule motor activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005815 [microtubule organizing center]
GO:0005828 [kinetochore microtubule]
GO:0005829 [cytosol]
GO:0005871 [kinesin complex]
GO:0005901 [caveola]
GO:0007018 [microtubule-based movement]
GO:0007019 [microtubule depolymerization]
GO:0007080 [mitotic metaphase plate congression]
GO:0007140 [male meiosis]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008574 [ATP-dependent microtubule motor activity, plus-end-directed]
GO:0015031 [protein transport]
GO:0015630 [microtubule cytoskeleton]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0043130 [ubiquitin binding]
GO:0051010 [microtubule plus-end binding]
GO:0070463 [tubulin-dependent ATPase activity]
GO:0070507 [regulation of microtubule cytoskeleton organization]
GO:0072520 [seminiferous tubule development]
GO:1990023 [mitotic spindle midzone]
Show all
 898 aa
102.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.