Cell atlas - BICC1 - The Human Protein Atlas

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BICC1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	BICC1
Gene description	BicC family RNA binding protein 1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (RPTEC TERT1, CACO-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA045212
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPTEC TERT1, CACO-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA045212	A-431	Nucleoplasm
	HPA045212	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	BICC1
Synonyms
Description	BicC family RNA binding protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product. [provided by RefSeq, Apr 2009]
Chromosome	10
Cytoband	q21.1
Chromosome location (bp)	58513140 - 58831437
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122870 (version 83.38)
Entrez gene	80114
UniProt	Q9H694 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H694
Antibodypedia	BICC1 antibodies

PROTEIN BROWSER

BICC1-001	BICC1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BICC1-001 ENSP00000263103 ENST00000263103	A6NGY7 [Direct mapping] Protein bicaudal C homolog 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		506 aa 53.3 kDa	No	0
BICC1-002 ENSP00000362993 ENST00000373886	Q9H694 [Direct mapping] Protein bicaudal C homolog 1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007275 [multicellular organismal development] GO:0007368 [determination of left/right symmetry] GO:0007507 [heart development] GO:0044822 [poly(A) RNA binding] GO:0090090 [negative regulation of canonical Wnt signaling pathway] Show all	974 aa 104.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.