Tissue expression of IL13RA2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	IL13RA2
Gene description	Interleukin 13 receptor, alpha 2
Protein class	Cancer-related genes CD markers Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Group enriched (hypothalamus, pituitary gland, testis)
FANTOM5:	Group enriched (caudate, pituitary gland, testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (hypothalamus, pituitary gland, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, pituitary gland, testis)

GENE INFORMATION
Gene name	IL13RA2 (HGNC Symbol)
Synonyms	CD213a2, CT19, IL-13R, IL13BP
Description	Interleukin 13 receptor, alpha 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q23
Chromosome location (bp)	115003975 - 115019977
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000123496 (version 83.38)
Entrez gene	3598
UniProt	Q14627 (UniProt - Evidence at protein level)
neXtProt	NX_Q14627
Antibodypedia	IL13RA2 antibodies

PROTEIN BROWSER

IL13RA2-001	IL13RA2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IL13RA2-001 ENSP00000361004 ENST00000371936	Q14627 [Direct mapping] Interleukin-13 receptor subunit alpha-2 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0002638 [negative regulation of immunoglobulin production] GO:0004871 [signal transducer activity] GO:0004896 [cytokine receptor activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016064 [immunoglobulin mediated immune response] GO:0019221 [cytokine-mediated signaling pathway] GO:0043305 [negative regulation of mast cell degranulation] GO:0071260 [cellular response to mechanical stimulus] Show all	380 aa 44.2 kDa	Yes	1
IL13RA2-201 ENSP00000243213 ENST00000243213	Q14627 [Direct mapping] Interleukin-13 receptor subunit alpha-2 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0004896 [cytokine receptor activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019221 [cytokine-mediated signaling pathway] Show all	380 aa 44.2 kDa	Yes	1