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DNPEP

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GENERAL INFORMATION

Gene name

 DNPEP

Gene description

 Aspartyl aminopeptidase

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 10
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the cytosol.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA044860
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the cytosol.

Main location

 Cytosol (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA044860 CACO-2 Cytosol
HPA044860 MCF7 Cytosol
HPA044860 U-2 OS No staining    

GENE INFORMATION

Gene name

 DNPEP (HGNC Symbol)

Synonyms

 ASPEP, DAP

Description

 Aspartyl aminopeptidase (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 219373546 - 219400022

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000123992 (version 83.38)

Entrez gene

 23549

UniProt

 Q9ULA0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9ULA0

Antibodypedia

 DNPEP antibodies

PROTEIN BROWSER
DNPEP-001
DNPEP-005
DNPEP-006
DNPEP-007
DNPEP-008
DNPEP-013
DNPEP-014
DNPEP-015
DNPEP-017
DNPEP-019

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DNPEP-001
ENSP00000273075
ENST00000273075
Q9ULA0 [Direct mapping]
Aspartyl aminopeptidase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
GO:0006518 [peptide metabolic process]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
GO:0072562 [blood microparticle]
Show all
 485 aa
53.4 kDa 		No 0
DNPEP-005
ENSP00000363083
ENST00000373972
E7EMB6 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 410 aa
45 kDa 		No 0
DNPEP-006
ENSP00000400944
ENST00000429013
F8WAN0 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 273 aa
30.3 kDa 		No 0
DNPEP-007
ENSP00000414739
ENST00000430206
C9JRG3 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 117 aa
13 kDa 		No 0
DNPEP-008
ENSP00000317252
ENST00000322176
B9ZVU2 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 270 aa
29.9 kDa 		No 0
DNPEP-013
ENSP00000410684
ENST00000457935
C9JBE1 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 331 aa
36.6 kDa 		No 0
DNPEP-014
ENSP00000412003
ENST00000434339
C9J1E2 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 138 aa
15.3 kDa 		No 0
DNPEP-015
ENSP00000431076
ENST00000523282
E7ETB3 [Direct mapping]
Aspartyl aminopeptidase; Aspartyl aminopeptidase, isoform CRA_c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 493 aa
54.5 kDa 		No 0
DNPEP-017
ENSP00000430630
ENST00000519905
E5RJ35 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008270 [zinc ion binding]
Show all
 89 aa
9.8 kDa 		No 0
DNPEP-019
ENSP00000429960
ENST00000521459
E7EPX3 [Direct mapping]
Aspartyl aminopeptidase
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004177 [aminopeptidase activity]
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 224 aa
24.9 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.