Tissue expression of RPP40 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RPP40
Gene description	Ribonuclease P/MRP 40kDa subunit
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA035685 , HPA035686
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RPP40 (HGNC Symbol)
Synonyms	bA428J1.3, RNASEP1
Description	Ribonuclease P/MRP 40kDa subunit (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p25.1
Chromosome location (bp)	4994732 - 5004063
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124787 (version 83.38)
Entrez gene	10799
UniProt	O75818 (UniProt - Evidence at protein level)
neXtProt	NX_O75818
Antibodypedia	RPP40 antibodies

PROTEIN BROWSER

RPP40-001	RPP40-002	RPP40-006	RPP40-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPP40-001 ENSP00000369391 ENST00000380051	O75818 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	363 aa 41.8 kDa	No	0
RPP40-002 ENSP00000317998 ENST00000319533	O75818 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	340 aa 39.3 kDa	No	0
RPP40-006 ENSP00000419431 ENST00000464646	X6RLL4 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		303 aa 34.7 kDa	No	0
RPP40-201 ENSP00000484334 ENST00000618533	A0A087X1N3 [Direct mapping] Ribonuclease P 40kDa subunit, isoform CRA_c; Ribonuclease P protein subunit p40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		321 aa 36.8 kDa	No	0