Cell atlas - CLYBL - The Human Protein Atlas

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CLYBL

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	CLYBL
Gene description	Citrate lyase beta like
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enhanced (SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA039959
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA039959	U-2 OS	Cytosol
	HPA039959	U-251 MG	Cytosol

GENE INFORMATION
Gene name	CLYBL (HGNC Symbol)
Synonyms	CLB
Description	Citrate lyase beta like (HGNC Symbol)
Entrez gene summary
Chromosome	13
Cytoband	q32.3
Chromosome location (bp)	99606669 - 99897134
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125246 (version 83.38)
Entrez gene	171425
UniProt	Q8N0X4 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N0X4
Antibodypedia	CLYBL antibodies

PROTEIN BROWSER

CLYBL-001	CLYBL-002	CLYBL-003	CLYBL-004	CLYBL-005	CLYBL-006	CLYBL-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLYBL-001 ENSP00000365533 ENST00000376355	Q8N0X4 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Enzymes ENZYME proteins Transferases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003824 [catalytic activity] GO:0004474 [malate synthase activity] GO:0005739 [mitochondrion] GO:0008152 [metabolic process] Show all	340 aa 37.4 kDa	No	0
CLYBL-002 ENSP00000365532 ENST00000376354	Q8N0X4 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Enzymes ENZYME proteins Transferases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003824 [catalytic activity] GO:0004474 [malate synthase activity] GO:0005739 [mitochondrion] GO:0008152 [metabolic process] Show all	306 aa 33.4 kDa	No	0
CLYBL-003 ENSP00000342991 ENST00000339105	Q8N0X4 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Enzymes ENZYME proteins Transferases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003824 [catalytic activity] GO:0004474 [malate synthase activity] GO:0005739 [mitochondrion] GO:0008152 [metabolic process] Show all	340 aa 37.4 kDa	No	0
CLYBL-004 ENSP00000403408 ENST00000416504	Q5JVC2 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	181 aa 20.2 kDa	No	1
CLYBL-005 ENSP00000401586 ENST00000443887	Q5JVC1 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	147 aa 16.3 kDa	No	1
CLYBL-006 ENSP00000389062 ENST00000425186	Q5JVB9 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		89 aa 10 kDa	No	0
CLYBL-007 ENSP00000396574 ENST00000419700	Q5JVC0 [Direct mapping] Citrate lyase subunit beta-like protein, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	103 aa 11.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.