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RRAS

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GENERAL INFORMATION

Gene name

 RRAS

Gene description

 Related RAS viral (r-ras) oncogene homolog

Protein class

 Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to vesicles.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Vesicles (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA060364
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to vesicles.

Main location

 Vesicles (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA060364 A549 Vesicles
HPA060364 PC-3 Vesicles
HPA060364 U-2 OS Vesicles

GENE INFORMATION

Gene name

 RRAS

Synonyms

Description

 Related RAS viral (r-ras) oncogene homolog (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

Chromosome

 19

Cytoband

 q13.33

Chromosome location (bp)

 49635292 - 49640201

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126458 (version 83.38)

Entrez gene

 6237

UniProt

 P10301 (UniProt - Evidence at protein level)

neXtProt

 NX_P10301

Antibodypedia

 RRAS antibodies

PROTEIN BROWSER
RRAS-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RRAS-001
ENSP00000246792
ENST00000246792
P10301 [Direct mapping]
Ras-related protein R-Ras
A0A024QZF2 [Target identity:100%; Query identity:100%]
Related RAS viral (R-ras) oncogene homolog, isoform CRA_a
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Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0002521 [leukocyte differentiation]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030336 [negative regulation of cell migration]
GO:0032403 [protein complex binding]
GO:0045766 [positive regulation of angiogenesis]
GO:0051896 [regulation of protein kinase B signaling]
GO:0060325 [face morphogenesis]
GO:0070062 [extracellular exosome]
GO:0070372 [regulation of ERK1 and ERK2 cascade]
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 218 aa
23.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.