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HTN1

GENERAL INFORMATION

Gene name

 HTN1

Gene description

 Histatin 1

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (salivary gland)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 HTN1 (HGNC Symbol)

Synonyms

 HIS1

Description

 Histatin 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing. [provided by RefSeq, Aug 2014]

Chromosome

 4

Cytoband

 q13.3

Chromosome location (bp)

 70050402 - 70058845

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126550 (version 83.38)

Entrez gene

 3346

UniProt

 P15515 (UniProt - Evidence at protein level)

neXtProt

 NX_P15515

Antibodypedia

 HTN1 antibodies

PROTEIN BROWSER
HTN1-001
HTN1-005
HTN1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HTN1-001
ENSP00000246896
ENST00000246896
P15515 [Direct mapping]
Histatin-1 His1-(31-57)-peptide
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0031214 [biomineral tissue development]
GO:0031640 [killing of cells of other organism]
GO:0042742 [defense response to bacterium]
GO:0046848 [hydroxyapatite binding]
GO:0050832 [defense response to fungus]
Show all
 57 aa
7 kDa 		Yes 0
HTN1-005
ENSP00000424501
ENST00000511674
P15515 [Direct mapping]
Histatin-1 His1-(31-57)-peptide
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0031214 [biomineral tissue development]
GO:0031640 [killing of cells of other organism]
GO:0042742 [defense response to bacterium]
GO:0046848 [hydroxyapatite binding]
GO:0050832 [defense response to fungus]
Show all
 57 aa
7 kDa 		Yes 0
HTN1-201
ENSP00000482787
ENST00000610341
P15515 [Direct mapping]
Histatin-1 His1-(31-57)-peptide
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0031214 [biomineral tissue development]
GO:0031640 [killing of cells of other organism]
GO:0042742 [defense response to bacterium]
GO:0046848 [hydroxyapatite binding]
GO:0050832 [defense response to fungus]
Show all
 57 aa
7 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.