Tissue expression of HTN1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	HTN1
Gene description	Histatin 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (salivary gland)
GTEx:	Tissue enriched (salivary gland)
FANTOM5:	Tissue enriched (salivary gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)

GENE INFORMATION
Gene name	HTN1 (HGNC Symbol)
Synonyms	HIS1
Description	Histatin 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing. [provided by RefSeq, Aug 2014]
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	70050402 - 70058845
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126550 (version 83.38)
Entrez gene	3346
UniProt	P15515 (UniProt - Evidence at protein level)
neXtProt	NX_P15515
Antibodypedia	HTN1 antibodies

PROTEIN BROWSER

HTN1-001	HTN1-005	HTN1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HTN1-001 ENSP00000246896 ENST00000246896	P15515 [Direct mapping] Histatin-1 His1-(31-57)-peptide Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0031214 [biomineral tissue development] GO:0031640 [killing of cells of other organism] GO:0042742 [defense response to bacterium] GO:0046848 [hydroxyapatite binding] GO:0050832 [defense response to fungus] Show all	57 aa 7 kDa	Yes	0
HTN1-005 ENSP00000424501 ENST00000511674	P15515 [Direct mapping] Histatin-1 His1-(31-57)-peptide Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0031214 [biomineral tissue development] GO:0031640 [killing of cells of other organism] GO:0042742 [defense response to bacterium] GO:0046848 [hydroxyapatite binding] GO:0050832 [defense response to fungus] Show all	57 aa 7 kDa	Yes	0
HTN1-201 ENSP00000482787 ENST00000610341	P15515 [Direct mapping] Histatin-1 His1-(31-57)-peptide Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0031214 [biomineral tissue development] GO:0031640 [killing of cells of other organism] GO:0042742 [defense response to bacterium] GO:0046848 [hydroxyapatite binding] GO:0050832 [defense response to fungus] Show all	57 aa 7 kDa	Yes	0