Cell atlas - PRDM7 - The Human Protein Atlas

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PRDM7

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear speckles

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	PRDM7
Gene description	PR domain containing 7
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear speckles.
RNA cell category	Group enriched (REH, SK-MEL-30)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA059944
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (REH, SK-MEL-30) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear speckles.

Main location

Nuclear speckles (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA059944	CACO-2	Nuclear speckles
	HPA059944	SK-MEL-30	Nuclear speckles
	HPA059944	U-2 OS	Nuclear speckles

GENE INFORMATION
Gene name	PRDM7 (HGNC Symbol)
Synonyms	ZNF910
Description	PR domain containing 7 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]
Chromosome	16
Cytoband	q24.3
Chromosome location (bp)	90056566 - 90092072
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126856 (version 83.38)
Entrez gene	11105
UniProt	Q9NQW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQW5
Antibodypedia	PRDM7 antibodies

PROTEIN BROWSER

PRDM7-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRDM7-002 ENSP00000396732 ENST00000449207	Q9NQW5 [Direct mapping] Probable histone-lysine N-methyltransferase PRDM7 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005694 [chromosome] GO:0006355 [regulation of transcription, DNA-templated] GO:0018024 [histone-lysine N-methyltransferase activity] GO:0034968 [histone lysine methylation] Show all	492 aa 55.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.