Expression of PRDM7 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PRDM7

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRDM7
Gene description	PR domain containing 7
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (melanoma)
HPA (cell line):	Group enriched (REH, SK-MEL-30)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expression in acrosomes in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA059944
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (melanoma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA059944

GENE INFORMATION
Gene name	PRDM7 (HGNC Symbol)
Synonyms	ZNF910
Description	PR domain containing 7 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]
Chromosome	16
Cytoband	q24.3
Chromosome location (bp)	90056566 - 90092072
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126856 (version 83.38)
Entrez gene	11105
UniProt	Q9NQW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQW5
Antibodypedia	PRDM7 antibodies

PROTEIN BROWSER

PRDM7-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRDM7-002 ENSP00000396732 ENST00000449207	Q9NQW5 [Direct mapping] Probable histone-lysine N-methyltransferase PRDM7 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005694 [chromosome] GO:0006355 [regulation of transcription, DNA-templated] GO:0018024 [histone-lysine N-methyltransferase activity] GO:0034968 [histone lysine methylation] Show all	492 aa 55.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.