Cell atlas - TRPV5 - The Human Protein Atlas

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TRPV5

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	TRPV5
Gene description	Transient receptor potential cation channel, subfamily V, member 5
Protein class	Predicted membrane proteins Transporters Voltage-gated ion channels
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TRPV5 (HGNC Symbol)
Synonyms	CaT2, ECAC1
Description	Transient receptor potential cation channel, subfamily V, member 5 (HGNC Symbol)
Entrez gene summary	This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q34
Chromosome location (bp)	142908101 - 142933808
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000127412 (version 83.38)
Entrez gene	56302
UniProt	Q9NQA5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQA5
Antibodypedia	TRPV5 antibodies

PROTEIN BROWSER

TRPV5-001	TRPV5-002	TRPV5-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRPV5-001 ENSP00000265310 ENST00000265310	A0A0A6YY98 [Direct mapping] Transient receptor potential cation channel subfamily V member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0006811 [ion transport] GO:0006816 [calcium ion transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] GO:0051262 [protein tetramerization] GO:0055085 [transmembrane transport] GO:0060402 [calcium ion transport into cytosol] GO:0070588 [calcium ion transmembrane transport] Show all	729 aa 82.6 kDa	No	6
TRPV5-002 ENSP00000406572 ENST00000442623	Q9NQA5 [Direct mapping] Transient receptor potential cation channel subfamily V member 5 Show all	Transporters Transporter channels and pores Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006816 [calcium ion transport] GO:0016324 [apical plasma membrane] GO:0034220 [ion transmembrane transport] GO:0051262 [protein tetramerization] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] Show all	381 aa 43.2 kDa	No	1
TRPV5-003 ENSP00000406361 ENST00000439304	H7C2J6 [Direct mapping] Transient receptor potential cation channel subfamily V member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0006811 [ion transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] Show all	674 aa 76 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.