Tissue expression of AAMP - Summary - The Human Protein Atlas

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AAMP

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	AAMP
Gene description	Angio-associated, migratory cell protein
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, most abundant in smooth muscle.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. CAB017717
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Small intestine

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	AAMP
Synonyms
Description	Angio-associated, migratory cell protein (HGNC Symbol)
Entrez gene summary	The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]
Chromosome	2
Cytoband	q35
Chromosome location (bp)	218264123 - 218270257
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000127837 (version 83.38)
Entrez gene	14
UniProt	Q13685 (UniProt - Evidence at protein level)
neXtProt	NX_Q13685
Antibodypedia	AAMP antibodies

PROTEIN BROWSER

AAMP-001	AAMP-002	AAMP-005	AAMP-007	AAMP-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AAMP-001 ENSP00000248450 ENST00000248450	Q13685 [Direct mapping] Angio-associated migratory cell protein A0A024R410 [Target identity:100%; Query identity:100%] Angio-associated, migratory cell protein, isoform CRA_b Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001525 [angiogenesis] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0008201 [heparin binding] GO:0009986 [cell surface] GO:0010595 [positive regulation of endothelial cell migration] GO:0014909 [smooth muscle cell migration] GO:0030154 [cell differentiation] Show all	434 aa 46.8 kDa	No	0
AAMP-002 ENSP00000403343 ENST00000444053	C9JEH3 [Direct mapping] Angio-associated migratory cell protein; Angio-associated, migratory cell protein, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	435 aa 46.8 kDa	No	0
AAMP-005 ENSP00000416394 ENST00000420660	C9JG97 [Direct mapping] Angio-associated migratory cell protein Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	415 aa 44.7 kDa	No	0
AAMP-007 ENSP00000393818 ENST00000447885	C9JTS3 [Direct mapping] Angio-associated migratory cell protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	201 aa 22 kDa	No	0
AAMP-009 ENSP00000396295 ENST00000422731	H7C0R2 [Direct mapping] Angio-associated migratory cell protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	189 aa 20 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.