Tissue expression of ADM2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ADM2
Gene description	Adrenomedullin 2
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (thyroid gland)
GTEx:	Tissue enhanced (thyroid gland)
FANTOM5:	Tissue enhanced (pancreas)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas)

GENE INFORMATION
Gene name	ADM2 (HGNC Symbol)
Synonyms	AM2, FLJ21135
Description	Adrenomedullin 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]
Chromosome	22
Cytoband	q13.33
Chromosome location (bp)	50481556 - 50486440
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000128165 (version 83.38)
Entrez gene	79924
UniProt	Q7Z4H4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z4H4
Antibodypedia	ADM2 antibodies

PROTEIN BROWSER

ADM2-001	ADM2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADM2-001 ENSP00000379087 ENST00000395738	Q7Z4H4 [Direct mapping] ADM2 Adrenomedullin-2 Intermedin-short Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0001525 [angiogenesis] GO:0005179 [hormone activity] GO:0005576 [extracellular region] GO:0006468 [protein phosphorylation] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0007586 [digestion] GO:0007631 [feeding behavior] GO:0010628 [positive regulation of gene expression] GO:0032403 [protein complex binding] GO:0045766 [positive regulation of angiogenesis] GO:0045776 [negative regulation of blood pressure] Show all	148 aa 15.9 kDa	Yes	0
ADM2-002 ENSP00000379086 ENST00000395737	Q7Z4H4 [Direct mapping] ADM2 Adrenomedullin-2 Intermedin-short Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0001525 [angiogenesis] GO:0005179 [hormone activity] GO:0005576 [extracellular region] GO:0006468 [protein phosphorylation] GO:0010628 [positive regulation of gene expression] GO:0032403 [protein complex binding] GO:0045766 [positive regulation of angiogenesis] Show all	148 aa 15.9 kDa	Yes	0