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A4GALT
  • TISSUE

  • premium

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  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

A4GALT

Gene description

Alpha 1,4-galactosyltransferase

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

A4GALT (HGNC Symbol)

Synonyms

A14GALT, Gb3S, P(k)

Description

Alpha 1,4-galactosyltransferase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q13.2

Chromosome location (bp)

42692121 - 42721298

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128274 (version 83.38)

Entrez gene

53947

UniProt

Q9NPC4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NPC4

Antibodypedia

A4GALT antibodies

PROTEIN BROWSER

A4GALT-001
A4GALT-003
A4GALT-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

A4GALT-001
ENSP00000249005
ENST00000249005
Q9NPC4 [Direct mapping]
Lactosylceramide 4-alpha-galactosyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006486 [protein glycosylation]
GO:0006688 [glycosphingolipid biosynthetic process]
GO:0007009 [plasma membrane organization]
GO:0008378 [galactosyltransferase activity]
GO:0016020 [membrane]
GO:0030173 [integral component of Golgi membrane]
GO:0050512 [lactosylceramide 4-alpha-galactosyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
353 aa
40.5 kDa
No 1
A4GALT-003
ENSP00000370678
ENST00000381278
Q9NPC4 [Direct mapping]
Lactosylceramide 4-alpha-galactosyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006486 [protein glycosylation]
GO:0006688 [glycosphingolipid biosynthetic process]
GO:0007009 [plasma membrane organization]
GO:0008378 [galactosyltransferase activity]
GO:0016020 [membrane]
GO:0030173 [integral component of Golgi membrane]
GO:0050512 [lactosylceramide 4-alpha-galactosyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
353 aa
40.5 kDa
No 1
A4GALT-004
ENSP00000384794
ENST00000401850
Q9NPC4 [Direct mapping]
Lactosylceramide 4-alpha-galactosyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001576 [globoside biosynthetic process]
GO:0006486 [protein glycosylation]
GO:0006688 [glycosphingolipid biosynthetic process]
GO:0007009 [plasma membrane organization]
GO:0008378 [galactosyltransferase activity]
GO:0015643 [toxic substance binding]
GO:0016020 [membrane]
GO:0030173 [integral component of Golgi membrane]
GO:0050512 [lactosylceramide 4-alpha-galactosyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
353 aa
40.5 kDa
No 1

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