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RNF112

GENERAL INFORMATION

Gene name

 RNF112

Gene description

 Ring finger protein 112

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (cerebellum)
FANTOM5:Tissue enhanced (caudate, cerebellum)

Protein evidence

 Evidence at transcript level

Protein expression

 Cytoplasmic expression in Purkinje cells of cerebellum.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. External characterization data supports antibody staining.

Reliability score

 Approved based on 1 antibody.
HPA015970
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (caudate, cerebellum)

GENE INFORMATION

Gene name

 RNF112 (HGNC Symbol)

Synonyms

 BFP, ZNF179

Description

 Ring finger protein 112 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the RING finger protein family of transcription factors. The protein is primarily expressed in brain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 p11.2

Chromosome location (bp)

 19411125 - 19417276

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000128482 (version 83.38)

Entrez gene

 7732

UniProt

 Q9ULX5 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9ULX5

Antibodypedia

 RNF112 antibodies

PROTEIN BROWSER
RNF112-001
RNF112-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RNF112-001
ENSP00000454919
ENST00000461366
Q9ULX5 [Direct mapping]
RING finger protein 112
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
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GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0008152 [metabolic process]
GO:0008270 [zinc ion binding]
GO:0016021 [integral component of membrane]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045687 [positive regulation of glial cell differentiation]
GO:0046872 [metal ion binding]
GO:0071158 [positive regulation of cell cycle arrest]
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 631 aa
68.3 kDa 		No 1
RNF112-005
ENSP00000464134
ENST00000575165
J3QRB8 [Direct mapping]
RING finger protein 112
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Predicted intracellular proteins
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GO:0005515 [protein binding]
GO:0008270 [zinc ion binding]
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 123 aa
13.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.