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MYO1B

GENERAL INFORMATION

Gene name

 MYO1B

Gene description

 Myosin IB

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Membranous expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA013607 , HPA060144
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MYO1B (HGNC Symbol)

Synonyms

 myr1

Description

 Myosin IB (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q32.3

Chromosome location (bp)

 191245185 - 191425389

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000128641 (version 83.38)

Entrez gene

 4430

UniProt

 O43795 (UniProt - Evidence at protein level)

neXtProt

 NX_O43795

Antibodypedia

 MYO1B antibodies

PROTEIN BROWSER
MYO1B-001
MYO1B-002
MYO1B-003
MYO1B-005
MYO1B-008
MYO1B-009
MYO1B-010
MYO1B-011
MYO1B-012
MYO1B-015

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYO1B-001
ENSP00000306382
ENST00000304164
O43795 [Direct mapping]
Unconventional myosin-Ib
B0I1S9 [Target identity:100%; Query identity:100%]
MYO1B variant protein; Myosin IB, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000146 [microfilament motor activity]
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005547 [phosphatidylinositol-3,4,5-trisphosphate binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005884 [actin filament]
GO:0005886 [plasma membrane]
GO:0005903 [brush border]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0007015 [actin filament organization]
GO:0008152 [metabolic process]
GO:0010008 [endosome membrane]
GO:0016459 [myosin complex]
GO:0030048 [actin filament-based movement]
GO:0030175 [filopodium]
GO:0032588 [trans-Golgi network membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051015 [actin filament binding]
GO:0051017 [actin filament bundle assembly]
GO:0070062 [extracellular exosome]
GO:0071944 [cell periphery]
Show all
 1136 aa
132 kDa 		No 0
MYO1B-002
ENSP00000376130
ENST00000392316
E9PDF6 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 1107 aa
128.5 kDa 		No 0
MYO1B-003
ENSP00000341903
ENST00000339514
O43795 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000146 [microfilament motor activity]
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005547 [phosphatidylinositol-3,4,5-trisphosphate binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005884 [actin filament]
GO:0005886 [plasma membrane]
GO:0005903 [brush border]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0007015 [actin filament organization]
GO:0008152 [metabolic process]
GO:0010008 [endosome membrane]
GO:0016459 [myosin complex]
GO:0030048 [actin filament-based movement]
GO:0030175 [filopodium]
GO:0032588 [trans-Golgi network membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051015 [actin filament binding]
GO:0051017 [actin filament bundle assembly]
GO:0070062 [extracellular exosome]
GO:0071944 [cell periphery]
Show all
 1078 aa
125 kDa 		No 0
MYO1B-005
ENSP00000388140
ENST00000451437
E7EQD9 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 303 aa
34.1 kDa 		No 0
MYO1B-008
ENSP00000387610
ENST00000420448
C9K0I9 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 83 aa
9.7 kDa 		No 0
MYO1B-009
ENSP00000408454
ENST00000427152
H7C2Y7 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 192 aa
21.7 kDa 		No 0
MYO1B-010
ENSP00000376132
ENST00000392318
O43795 [Direct mapping]
Unconventional myosin-Ib
B0I1S9 [Target identity:100%; Query identity:100%]
MYO1B variant protein; Myosin IB, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000146 [microfilament motor activity]
GO:0003774 [motor activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005547 [phosphatidylinositol-3,4,5-trisphosphate binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005884 [actin filament]
GO:0005886 [plasma membrane]
GO:0005903 [brush border]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0007015 [actin filament organization]
GO:0008152 [metabolic process]
GO:0010008 [endosome membrane]
GO:0016459 [myosin complex]
GO:0030048 [actin filament-based movement]
GO:0030175 [filopodium]
GO:0030898 [actin-dependent ATPase activity]
GO:0032588 [trans-Golgi network membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051015 [actin filament binding]
GO:0051017 [actin filament bundle assembly]
GO:0070062 [extracellular exosome]
GO:0071944 [cell periphery]
Show all
 1136 aa
132 kDa 		No 0
MYO1B-011
ENSP00000401324
ENST00000418908
C9JYW1 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 163 aa
18.3 kDa 		No 0
MYO1B-012
ENSP00000399459
ENST00000438652
C9JUP5 [Direct mapping]
Unconventional myosin-Ib
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 149 aa
16.8 kDa 		No 0
MYO1B-015
ENSP00000489544
ENST00000634375
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0016459 [myosin complex]
Show all
 189 aa
22.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.