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Most malignant tissues showed weak to moderate cytoplasmic immunoreactivity. Several cases of hepatocellular carcinomas along with a few cases of lung, testicular and pancreatic cancers were strongly stained.
A few cases of hepatocellular carcinomas showed moderate to strong cytoplasmic staining while head and neck cancers and a single case of malignant carcinoid displayed nuclear positivity. A subset of tumor cells in a few cases of malignant gliomas, melanomas along with occasional cases of squamous cell carcinomas of cervix, skin, testis and urothelial cancers displayed moderate to strong nuclear staining. Remaining malignant tissues were weakly stained or negative.
GENE INFORMATION
Gene name
FAM64A (HGNC Symbol)
Synonyms
CATS, FLJ10156, FLJ10491, RCS1
Description
Family with sequence similarity 64, member A (HGNC Symbol)