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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM64A
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

FAM64A

Gene description

Family with sequence similarity 64, member A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

Uncertain based on 2 antibodies.
HPA043783 , HPA049934
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Pancreatic cancer

STAINING SUMMARY

HPA043783
HPA049934

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most malignant tissues showed weak to moderate cytoplasmic immunoreactivity. Several cases of hepatocellular carcinomas along with a few cases of lung, testicular and pancreatic cancers were strongly stained.

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A few cases of hepatocellular carcinomas showed moderate to strong cytoplasmic staining while head and neck cancers and a single case of malignant carcinoid displayed nuclear positivity. A subset of tumor cells in a few cases of malignant gliomas, melanomas along with occasional cases of squamous cell carcinomas of cervix, skin, testis and urothelial cancers displayed moderate to strong nuclear staining. Remaining malignant tissues were weakly stained or negative.

GENE INFORMATION

Gene name

FAM64A (HGNC Symbol)

Synonyms

CATS, FLJ10156, FLJ10491, RCS1

Description

Family with sequence similarity 64, member A (HGNC Symbol)

Entrez gene summary

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

6444415 - 6451469

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129195 (version 83.38)

Entrez gene

54478

UniProt

Q9BSJ6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BSJ6

Antibodypedia

FAM64A antibodies

PROTEIN BROWSER

FAM64A-003
FAM64A-006
FAM64A-008
FAM64A-009
FAM64A-012
FAM64A-013
FAM64A-014

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM64A-003
ENSP00000458584
ENST00000572595
I3L156 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
Show all
279 aa
30.9 kDa
No 0
FAM64A-006
ENSP00000459860
ENST00000571572
I3L2R2 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
130 aa
14.2 kDa
No 0
FAM64A-008
ENSP00000250056
ENST00000250056
Q9BSJ6 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0007067 [mitotic nuclear division]
GO:0051301 [cell division]
Show all
248 aa
27.5 kDa
No 0
FAM64A-009
ENSP00000459235
ENST00000572447
Q9BSJ6 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0007067 [mitotic nuclear division]
GO:0051301 [cell division]
Show all
238 aa
26.2 kDa
No 0
FAM64A-012
ENSP00000459597
ENST00000571373
I3L419 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
Show all
247 aa
27.2 kDa
No 0
FAM64A-013
ENSP00000460894
ENST00000570337
I3L419 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
Show all
247 aa
27.2 kDa
No 0
FAM64A-014
ENSP00000458534
ENST00000576056
Q9BSJ6 [Direct mapping]
Protein FAM64A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0007067 [mitotic nuclear division]
GO:0051301 [cell division]
Show all
238 aa
26.2 kDa
No 0

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