Expression of KRI1 in cancer - Summary - The Human Protein Atlas

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KRI1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KRI1
Gene description	KRI1 homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expressed in the cytoplasm and also in the nucleoli in most cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA043110 , HPA043574
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable) and colorectal cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Colorectal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043110	HPA043574

GENE INFORMATION
Gene name	KRI1 (HGNC Symbol)
Synonyms	FLJ12949
Description	KRI1 homolog (HGNC Symbol)
Entrez gene summary	This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	10553078 - 10566037
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129347 (version 83.38)
Entrez gene	65095
UniProt	Q8N9T8 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N9T8
Antibodypedia	KRI1 antibodies

PROTEIN BROWSER

KRI1-003	KRI1-004	KRI1-010	KRI1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRI1-003 ENSP00000412919 ENST00000432197	F8WFC1 [Direct mapping] Protein KRI1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		197 aa 23.3 kDa	No	0
KRI1-004 ENSP00000320917 ENST00000312962	Q8N9T8 [Direct mapping] Protein KRI1 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005730 [nucleolus] GO:0044822 [poly(A) RNA binding] Show all	709 aa 83.3 kDa	No	0
KRI1-010 ENSP00000438000 ENST00000543682	H0YFD2 [Direct mapping] Protein KRI1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		190 aa 22.2 kDa	No	0
KRI1-012 ENSP00000445789 ENST00000539027	H0YH26 [Direct mapping] Protein KRI1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		194 aa 23 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.