Tissue expression of TEP1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	TEP1
Gene description	Telomerase-associated protein 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TEP1 (HGNC Symbol)
Synonyms	p240, TLP1, TP1, TROVE1, VAULT2
Description	Telomerase-associated protein 1 (HGNC Symbol)
Entrez gene summary	This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. [provided by RefSeq, Jul 2008]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	20365667 - 20413429
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129566 (version 83.38)
Entrez gene	7011
UniProt	Q99973 (UniProt - Evidence at protein level)
neXtProt	NX_Q99973
Antibodypedia	TEP1 antibodies

PROTEIN BROWSER

TEP1-001	TEP1-003	TEP1-008	TEP1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TEP1-001 ENSP00000262715 ENST00000262715	Q99973 [Direct mapping] Telomerase protein component 1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000722 [telomere maintenance via recombination] GO:0000781 [chromosome, telomeric region] GO:0003720 [telomerase activity] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005697 [telomerase holoenzyme complex] GO:0005737 [cytoplasm] GO:0006278 [RNA-dependent DNA replication] GO:0016363 [nuclear matrix] GO:0030529 [ribonucleoprotein complex] Show all	2627 aa 290.5 kDa	No	0
TEP1-003 ENSP00000452574 ENST00000556935	G3V5X7 [Direct mapping] Telomerase protein component 1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003723 [RNA binding] GO:0005515 [protein binding] Show all	2519 aa 278 kDa	No	0
TEP1-008 ENSP00000452240 ENST00000556549	G3V591 [Direct mapping] Telomerase protein component 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		166 aa 18.4 kDa	No	0
TEP1-011 ENSP00000450508 ENST00000553984	H0YIZ2 [Direct mapping] Telomerase protein component 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		201 aa 21.9 kDa	No	0