Tissue expression of PHF10 - Summary - The Human Protein Atlas

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PHF10

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PHF10
Gene description	PHD finger protein 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 1 antibody. HPA055649
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PHF10 (HGNC Symbol)
Synonyms	BAF45a, FLJ10975, XAP135
Description	PHD finger protein 10 (HGNC Symbol)
Entrez gene summary	This gene contains a predicted ORF that encodes a protein with two zinc finger domains. The function of the encoded protein is not known. Sequence analysis suggests that multiple alternatively spliced transcript variants are derived from this gene but the full-length nature of only two of them is known. These two splice variants encode different isoforms. A pseudogene for this gene is located on Xq28. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	q27
Chromosome location (bp)	169703905 - 169725566
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130024 (version 83.38)
Entrez gene	55274
UniProt	Q8WUB8 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WUB8
Antibodypedia	PHF10 antibodies

PROTEIN BROWSER

PHF10-001	PHF10-002	PHF10-201	PHF10-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PHF10-001 ENSP00000341805 ENST00000339209	Q8WUB8 [Direct mapping] PHD finger protein 10 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008270 [zinc ion binding] GO:0071564 [npBAF complex] Show all	498 aa 56.1 kDa	No	0
PHF10-002 ENSP00000355743 ENST00000366780	Q8WUB8 [Direct mapping] PHD finger protein 10 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008270 [zinc ion binding] GO:0071564 [npBAF complex] Show all	496 aa 55.8 kDa	No	0
PHF10-201 ENSP00000479515 ENST00000612128	S5FZ81 [Direct mapping] PHD finger protein 10; PHF10 isoform Sl Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		377 aa 42.6 kDa	No	0
PHF10-202 ENSP00000484117 ENST00000621772	Q8WUB8 [Direct mapping] PHD finger protein 10 S5FMB0 [Target identity:100%; Query identity:100%] PHF10 isoform Ps Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008270 [zinc ion binding] GO:0071564 [npBAF complex] Show all	451 aa 51.3 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.