We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cancer cells exhibited mainly weak to moderate granular cytoplasmic immunoreactivity. Several cases of colorectal cancers showed strong staining. Most testicular, urothelial and breast carcinomas were negative.
GENE INFORMATION
Gene name
MAS1
Synonyms
Description
MAS1 proto-oncogene, G protein-coupled receptor (HGNC Symbol)
Entrez gene summary
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]