Cell atlas - BMP15 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

BMP15

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	BMP15
Gene description	Bone morphogenetic protein 15
Protein class	Disease related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BMP15 (HGNC Symbol)
Synonyms	GDF9B
Description	Bone morphogenetic protein 15 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	50910784 - 50916607
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130385 (version 83.38)
Entrez gene	9210
UniProt	O95972 (UniProt - Evidence at protein level)
neXtProt	NX_O95972
Antibodypedia	BMP15 antibodies

PROTEIN BROWSER

BMP15-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMP15-001 ENSP00000252677 ENST00000252677	O95972 [Direct mapping] Bone morphogenetic protein 15 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0001541 [ovarian follicle development] GO:0005125 [cytokine activity] GO:0005160 [transforming growth factor beta receptor binding] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0007292 [female gamete generation] GO:0008083 [growth factor activity] GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation] GO:0030509 [BMP signaling pathway] GO:0042981 [regulation of apoptotic process] GO:0043408 [regulation of MAPK cascade] GO:0048468 [cell development] GO:0060016 [granulosa cell development] GO:0060395 [SMAD protein signal transduction] Show all	392 aa 45.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.