Tissue expression of BMP15 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	BMP15
Gene description	Bone morphogenetic protein 15
Protein class	Disease related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
GTEx:	Not detected

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	BMP15 (HGNC Symbol)
Synonyms	GDF9B
Description	Bone morphogenetic protein 15 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	50910784 - 50916607
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130385 (version 83.38)
Entrez gene	9210
UniProt	O95972 (UniProt - Evidence at protein level)
neXtProt	NX_O95972
Antibodypedia	BMP15 antibodies

PROTEIN BROWSER

BMP15-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMP15-001 ENSP00000252677 ENST00000252677	O95972 [Direct mapping] Bone morphogenetic protein 15 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0001541 [ovarian follicle development] GO:0005125 [cytokine activity] GO:0005160 [transforming growth factor beta receptor binding] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0007292 [female gamete generation] GO:0008083 [growth factor activity] GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation] GO:0030509 [BMP signaling pathway] GO:0042981 [regulation of apoptotic process] GO:0043408 [regulation of MAPK cascade] GO:0048468 [cell development] GO:0060016 [granulosa cell development] GO:0060395 [SMAD protein signal transduction] Show all	392 aa 45.1 kDa	Yes	0