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A few cases of melanomas, ovarian and thyroid cancers displayed moderate to strong cytoplasmic and nuclear staining. Remaining cancer tissues along with stromal cells were negative.
GENE INFORMATION
Gene name
HELZ2 (HGNC Symbol)
Synonyms
KIAA1769, PDIP1, PRIC285
Description
Helicase with zinc finger 2, transcriptional coactivator (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Q9BYK8 [Direct mapping] Helicase with zinc finger domain 2
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SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)