Tissue expression of GATA5 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	GATA5
Gene description	GATA binding protein 5
Protein class	Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (duodenum, small intestine, testis)
GTEx:	Tissue enhanced (testis, urinary bladder)
FANTOM5:	Tissue enhanced (small intestine, testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (duodenum, small intestine, testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis, urinary bladder)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine, testis)

GENE INFORMATION
Gene name	GATA5 (HGNC Symbol)
Synonyms	bB379O24.1, GATAS
Description	GATA binding protein 5 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q13.33
Chromosome location (bp)	62463497 - 62475970
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130700 (version 83.38)
Entrez gene	140628
UniProt	Q9BWX5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWX5
Antibodypedia	GATA5 antibodies

PROTEIN BROWSER

GATA5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GATA5-001 ENSP00000252997 ENST00000252997	Q9BWX5 [Direct mapping] Transcription factor GATA-5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001085 [RNA polymerase II transcription factor binding] GO:0001158 [enhancer sequence-specific DNA binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007507 [heart development] GO:0007596 [blood coagulation] GO:0008270 [zinc ion binding] GO:0009887 [organ morphogenesis] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045165 [cell fate commitment] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048468 [cell development] GO:0048646 [anatomical structure formation involved in morphogenesis] GO:0060575 [intestinal epithelial cell differentiation] GO:0071773 [cellular response to BMP stimulus] Show all	397 aa 41.3 kDa	No	0