Cell atlas - AAR2 - The Human Protein Atlas

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AAR2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	AAR2
Gene description	AAR2 splicing factor homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA048645
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA048645	CACO-2	Cytosol
	HPA048645	MCF7	No staining
	HPA048645	U-2 OS	Cytosol

MOUSE CELLS

Main location

Not available

Mouse gene

ENSMUSG00000027628 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA048645	NIH 3T3	No staining

GENE INFORMATION
Gene name	AAR2 (HGNC Symbol)
Synonyms	bA234K24.2, C20orf4
Description	AAR2 splicing factor homolog (HGNC Symbol)
Entrez gene summary	This gene encodes the homolog of the yeast A1-alpha2 repressin protein that is involved in mRNA splicing. Alternately spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Chromosome	20
Cytoband	q11.23
Chromosome location (bp)	36236459 - 36270918
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131043 (version 83.38)
Entrez gene	25980
UniProt	Q9Y312 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y312
Antibodypedia	AAR2 antibodies

PROTEIN BROWSER

AAR2-001	AAR2-002	AAR2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AAR2-001 ENSP00000363043 ENST00000373932	Q9Y312 [Direct mapping] Protein AAR2 homolog Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000244 [spliceosomal tri-snRNP complex assembly] Show all	384 aa 43.5 kDa	No	0
AAR2-002 ENSP00000380455 ENST00000397286	A2A2Q9 [Direct mapping] Protein AAR2 homolog Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000244 [spliceosomal tri-snRNP complex assembly] Show all	398 aa 45 kDa	No	0
AAR2-003 ENSP00000313674 ENST00000320849	Q9Y312 [Direct mapping] Protein AAR2 homolog Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000244 [spliceosomal tri-snRNP complex assembly] Show all	384 aa 43.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.