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RBM39

GENERAL INFORMATION

Gene name

 RBM39

Gene description

 RNA binding motif protein 39

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA001591
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA001591

GENE INFORMATION

Gene name

 RBM39 (HGNC Symbol)

Synonyms

 CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2

Description

 RNA binding motif protein 39 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011]

Chromosome

 20

Cytoband

 q11.22

Chromosome location (bp)

 35703609 - 35742312

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000131051 (version 83.38)

Entrez gene

 9584

UniProt

 Q14498 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14498

Antibodypedia

 RBM39 antibodies

PROTEIN BROWSER
RBM39-001
RBM39-002
RBM39-013
RBM39-015
RBM39-018
RBM39-020
RBM39-035
RBM39-039

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBM39-001
ENSP00000354437
ENST00000361162
Q14498 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0006397 [mRNA processing]
GO:0008380 [RNA splicing]
GO:0015630 [microtubule cytoskeleton]
GO:0016607 [nuclear speck]
GO:0044822 [poly(A) RNA binding]
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 524 aa
58.7 kDa 		No 0
RBM39-002
ENSP00000253363
ENST00000253363
Q14498 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0006397 [mRNA processing]
GO:0008380 [RNA splicing]
GO:0015630 [microtubule cytoskeleton]
GO:0016607 [nuclear speck]
GO:0044822 [poly(A) RNA binding]
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 530 aa
59.4 kDa 		No 0
RBM39-013
ENSP00000380527
ENST00000397370
A8MYG5 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 95 aa
10.9 kDa 		No 0
RBM39-015
ENSP00000436747
ENST00000528062
Q14498 [Direct mapping]
RNA-binding protein 39
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006396 [RNA processing]
GO:0006397 [mRNA processing]
GO:0008380 [RNA splicing]
GO:0015630 [microtubule cytoskeleton]
GO:0016607 [nuclear speck]
GO:0044822 [poly(A) RNA binding]
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 508 aa
57.1 kDa 		No 0
RBM39-018
ENSP00000393493
ENST00000434927
Q5QP22 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000166 [nucleotide binding]
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 193 aa
23.1 kDa 		No 0
RBM39-020
ENSP00000363150
ENST00000374038
Q5QP23 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
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 231 aa
27.1 kDa 		No 0
RBM39-035
ENSP00000394824
ENST00000448303
H0Y4X3 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
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 337 aa
36.6 kDa 		No 0
RBM39-039
ENSP00000405916
ENST00000426951
H0Y6I9 [Direct mapping]
RNA-binding protein 39
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 86 aa
10.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.