Most malignant tissues displayed moderate nuclear immunoreactivity. Strong staining was observed in thyroid cancers and in few malignant lymphomas, urothelial cancers and malignant gliomas.
RBM39 (HGNC Symbol)
CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2
RNA binding motif protein 39 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011]