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HAUS8

GENERAL INFORMATION

Gene name

 HAUS8

Gene description

 HAUS augmin-like complex, subunit 8

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA039406
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 HAUS8 (HGNC Symbol)

Synonyms

 HICE1, MGC20533, NY-SAR-48

Description

 HAUS augmin-like complex, subunit 8 (HGNC Symbol)

Entrez gene summary

 HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 17049729 - 17075625

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000131351 (version 83.38)

Entrez gene

 93323

UniProt

 Q9BT25 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BT25

Antibodypedia

 HAUS8 antibodies

PROTEIN BROWSER
HAUS8-001
HAUS8-002
HAUS8-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HAUS8-001
ENSP00000253669
ENST00000253669
Q9BT25 [Direct mapping]
HAUS augmin-like complex subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000922 [spindle pole]
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005880 [nuclear microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 410 aa
44.9 kDa 		No 0
HAUS8-002
ENSP00000470829
ENST00000593360
Q9BT25 [Direct mapping]
HAUS augmin-like complex subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000922 [spindle pole]
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005880 [nuclear microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 349 aa
38.5 kDa 		No 0
HAUS8-004
ENSP00000395298
ENST00000448593
Q9BT25 [Direct mapping]
HAUS augmin-like complex subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000922 [spindle pole]
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005880 [nuclear microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 409 aa
44.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.