Cell atlas - SEC61G - The Human Protein Atlas

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SEC61G

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SEC61G
Gene description	Sec61 translocon gamma subunit
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SEC61G (HGNC Symbol)
Synonyms	SSS1
Description	Sec61 translocon gamma subunit (HGNC Symbol)
Entrez gene summary	The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p11.2
Chromosome location (bp)	54752250 - 54759974
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132432 (version 83.38)
Entrez gene	23480
UniProt	P60059 (UniProt - Evidence at protein level)
neXtProt	NX_P60059
Antibodypedia	SEC61G antibodies

PROTEIN BROWSER

SEC61G-001	SEC61G-002	SEC61G-005	SEC61G-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEC61G-001 ENSP00000388337 ENST00000415949	P60059 [Direct mapping] Protein transport protein Sec61 subunit gamma A0A024QYZ0 [Target identity:100%; Query identity:100%] Sec61 gamma subunit, isoform CRA_a Show all	Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006605 [protein targeting] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006886 [intracellular protein transport] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0015031 [protein transport] GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER] GO:0071806 [protein transmembrane transport] Show all	68 aa 7.7 kDa	No	1
SEC61G-002 ENSP00000378906 ENST00000395535	P60059 [Direct mapping] Protein transport protein Sec61 subunit gamma A0A024QYZ0 [Target identity:100%; Query identity:100%] Sec61 gamma subunit, isoform CRA_a Show all	Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006605 [protein targeting] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006886 [intracellular protein transport] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0015031 [protein transport] GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER] GO:0071806 [protein transmembrane transport] Show all	68 aa 7.7 kDa	No	1
SEC61G-005 ENSP00000409884 ENST00000450622	P60059 [Direct mapping] Protein transport protein Sec61 subunit gamma A0A024QYZ0 [Target identity:100%; Query identity:100%] Sec61 gamma subunit, isoform CRA_a Show all	Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006605 [protein targeting] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006886 [intracellular protein transport] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0015031 [protein transport] GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER] GO:0071806 [protein transmembrane transport] Show all	68 aa 7.7 kDa	No	1
SEC61G-201 ENSP00000341538 ENST00000352861	P60059 [Direct mapping] Protein transport protein Sec61 subunit gamma A0A024QYZ0 [Target identity:100%; Query identity:100%] Sec61 gamma subunit, isoform CRA_a Show all	Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006605 [protein targeting] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006886 [intracellular protein transport] GO:0008565 [protein transporter activity] GO:0010467 [gene expression] GO:0015031 [protein transport] GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER] GO:0071806 [protein transmembrane transport] Show all	68 aa 7.7 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.