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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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CLEC10A
  • TISSUE

  • CELL

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

CLEC10A

Gene description

C-type lectin domain family 10, member A

Protein class

CD markers
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Mixed
GTEx:Mixed
FANTOM5:Tissue enhanced (lymph node)

Protein evidence

Evidence at transcript level

Protein expression

Cytoplasmic expression in several tissues, including lymphoid cells.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.

Reliability score

Approved based on 1 antibody.
HPA021937
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Appendix

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node)

GENE INFORMATION

Gene name

CLEC10A (HGNC Symbol)

Synonyms

CD301, CLECSF13, CLECSF14, HML, HML2

Description

C-type lectin domain family 10, member A (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

7074537 - 7080307

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000132514 (version 83.38)

Entrez gene

10462

UniProt

Q8IUN9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IUN9

Antibodypedia

CLEC10A antibodies

PROTEIN BROWSER

CLEC10A-001
CLEC10A-002
CLEC10A-003
CLEC10A-004
CLEC10A-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLEC10A-001
ENSP00000254868
ENST00000254868
Q8IUN9 [Direct mapping]
C-type lectin domain family 10 member A
Show all
CD markers
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0002250 [adaptive immune response]
GO:0005886 [plasma membrane]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0030246 [carbohydrate binding]
GO:0045087 [innate immune response]
Show all
316 aa
35.4 kDa
No 0
CLEC10A-002
ENSP00000414938
ENST00000416562
J3KR22 [Direct mapping]
C-type lectin domain family 10 member A
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
Show all
289 aa
32.6 kDa
No 1
CLEC10A-003
ENSP00000460252
ENST00000571664
Q8IUN9 [Direct mapping]
C-type lectin domain family 10 member A
Show all
CD markers
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0002250 [adaptive immune response]
GO:0005886 [plasma membrane]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0030246 [carbohydrate binding]
GO:0045087 [innate immune response]
Show all
292 aa
32.9 kDa
No 0
CLEC10A-004
ENSP00000458728
ENST00000576617
Q8IUN9 [Direct mapping]
C-type lectin domain family 10 member A
Show all
CD markers
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0002250 [adaptive immune response]
GO:0005886 [plasma membrane]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0030246 [carbohydrate binding]
GO:0045087 [innate immune response]
Show all
256 aa
28.9 kDa
No 0
CLEC10A-005
ENSP00000461800
ENST00000576549
I3NI09 [Direct mapping]
C-type lectin domain family 10 member A
Show all
Predicted intracellular proteins
Show all
136 aa
15.3 kDa
No 0

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