Cell atlas - RHBG - The Human Protein Atlas

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RHBG

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	RHBG
Gene description	Rh family, B glycoprotein (gene/pseudogene)
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Group enriched (RT4, CACO-2, Hep G2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA042726
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (RT4, CACO-2, Hep G2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA042726	Hep G2	Nucleoplasm
	HPA042726	RT4	Nucleoplasm

GENE INFORMATION
Gene name	RHBG (HGNC Symbol)
Synonyms	SLC42A2
Description	Rh family, B glycoprotein (gene/pseudogene) (HGNC Symbol)
Entrez gene summary	This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Chromosome	1
Cytoband	q22
Chromosome location (bp)	156369212 - 156385219
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132677 (version 83.38)
Entrez gene	57127
UniProt	Q9H310 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H310
Antibodypedia	RHBG antibodies

PROTEIN BROWSER

RHBG-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RHBG-001 ENSP00000441197 ENST00000537040	Q9H310 [Direct mapping] Ammonium transporter Rh type B Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0008519 [ammonium transmembrane transporter activity] GO:0014731 [spectrin-associated cytoskeleton] GO:0015696 [ammonium transport] GO:0016020 [membrane] GO:0016323 [basolateral plasma membrane] GO:0030506 [ankyrin binding] GO:0030659 [cytoplasmic vesicle membrane] GO:0046658 [anchored component of plasma membrane] GO:0055085 [transmembrane transport] GO:0070634 [transepithelial ammonium transport] GO:0072488 [ammonium transmembrane transport] Show all	458 aa 49.5 kDa	No	>9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.