Fields »
ABOUT
HELP
BLOG
HAPLN2

GENERAL INFORMATION

Gene name

 HAPLN2

Gene description

 Hyaluronan and proteoglycan link protein 2

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus)
FANTOM5:Group enriched (brain, caudate, cerebellum, hippocampus)

Protein evidence

 Evidence at protein level

Protein expression

 Distinct expression in processes in CNS

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA045765
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Caudate

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus)

GENE INFORMATION

Gene name

 HAPLN2 (HGNC Symbol)

Synonyms

 BRAL1

Description

 Hyaluronan and proteoglycan link protein 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q23.1

Chromosome location (bp)

 156619294 - 156625725

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132702 (version 83.38)

Entrez gene

 60484

UniProt

 Q9GZV7 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9GZV7

Antibodypedia

 HAPLN2 antibodies

PROTEIN BROWSER
HAPLN2-001
HAPLN2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HAPLN2-001
ENSP00000255039
ENST00000255039
Q9GZV7 [Direct mapping]
Hyaluronan and proteoglycan link protein 2
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001501 [skeletal system development]
GO:0005515 [protein binding]
GO:0005540 [hyaluronic acid binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0007155 [cell adhesion]
GO:0007417 [central nervous system development]
GO:0008065 [establishment of blood-nerve barrier]
GO:0085029 [extracellular matrix assembly]
Show all
 340 aa
37.8 kDa 		Yes 0
HAPLN2-004
ENSP00000388835
ENST00000456112
Q5T3J1 [Direct mapping]
Hyaluronan and proteoglycan link protein 2
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001501 [skeletal system development]
GO:0005515 [protein binding]
GO:0005540 [hyaluronic acid binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0007155 [cell adhesion]
GO:0007417 [central nervous system development]
Show all
 185 aa
20.8 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.