Cell atlas - ALDH3B2 - The Human Protein Atlas

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ALDH3B2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ALDH3B2
Gene description	Aldehyde dehydrogenase 3 family, member B2
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (MCF7, SK-BR-3)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (MCF7, SK-BR-3) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ALDH3B2 (HGNC Symbol)
Synonyms	ALDH8
Description	Aldehyde dehydrogenase 3 family, member B2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	67662162 - 67681200
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132746 (version 83.38)
Entrez gene	222
UniProt	P48448 (UniProt - Evidence at transcript level)
neXtProt	NX_P48448
Antibodypedia	ALDH3B2 antibodies

PROTEIN BROWSER

ALDH3B2-001	ALDH3B2-004	ALDH3B2-007	ALDH3B2-008	ALDH3B2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ALDH3B2-001 ENSP00000431595 ENST00000530069	P48448 [Direct mapping] Aldehyde dehydrogenase family 3 member B2 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004028 [3-chloroallyl aldehyde dehydrogenase activity] GO:0004029 [aldehyde dehydrogenase (NAD) activity] GO:0004030 [aldehyde dehydrogenase [NAD(P)+] activity] GO:0006066 [alcohol metabolic process] GO:0006068 [ethanol catabolic process] GO:0006629 [lipid metabolic process] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	385 aa 42.6 kDa	No	2
ALDH3B2-004 ENSP00000433718 ENST00000525827	E9PJV0 [Direct mapping] Aldehyde dehydrogenase family 3 member B2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004029 [aldehyde dehydrogenase (NAD) activity] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	148 aa 16.1 kDa	No	2
ALDH3B2-007 ENSP00000433466 ENST00000528756	E9PKY9 [Direct mapping] Aldehyde dehydrogenase family 3 member B2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004029 [aldehyde dehydrogenase (NAD) activity] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	95 aa 10.4 kDa	No	0
ALDH3B2-008 ENSP00000435476 ENST00000531248	H0YEC0 [Direct mapping] Aldehyde dehydrogenase family 3 member B2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004029 [aldehyde dehydrogenase (NAD) activity] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	128 aa 14 kDa	No	0
ALDH3B2-201 ENSP00000255084 ENST00000349015	P48448 [Direct mapping] Aldehyde dehydrogenase family 3 member B2 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004028 [3-chloroallyl aldehyde dehydrogenase activity] GO:0004029 [aldehyde dehydrogenase (NAD) activity] GO:0004030 [aldehyde dehydrogenase [NAD(P)+] activity] GO:0006066 [alcohol metabolic process] GO:0006068 [ethanol catabolic process] GO:0006629 [lipid metabolic process] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	385 aa 42.6 kDa	No	2

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.