Cell atlas - MYO18B - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MYO18B

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Nucleoplasm

Human cell
	Centrosome
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	MYO18B
Gene description	Myosin XVIIIB
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the centrosome & nucleoplasm.
RNA cell category	Cell line enhanced (RH-30, U-2 OS, REH, HDLM-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported), Centrosome (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA000953
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RH-30, U-2 OS, REH, HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the centrosome & nucleoplasm.

Main location

Nucleoplasm (supported), Centrosome (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA000953	RH-30	Nucleoplasm
	HPA000953	RH-30	Centrosome

GENE INFORMATION
Gene name	MYO18B (HGNC Symbol)
Synonyms	BK125H2.1
Description	Myosin XVIIIB (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband	q12.1
Chromosome location (bp)	25742144 - 26031041
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133454 (version 83.38)
Entrez gene	84700
UniProt
neXtProt
Antibodypedia	MYO18B antibodies

PROTEIN BROWSER

MYO18B-001	MYO18B-003	MYO18B-006	MYO18B-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYO18B-001 ENSP00000334563 ENST00000335473	A0A075B6F5 [Direct mapping] Unconventional myosin-XVIIIb Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001570 [vasculogenesis] GO:0001701 [in utero embryonic development] GO:0003774 [motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0008152 [metabolic process] GO:0016459 [myosin complex] GO:0030018 [Z disc] GO:0031941 [filamentous actin] GO:0048739 [cardiac muscle fiber development] Show all	2567 aa 285.2 kDa	No	0
MYO18B-003 ENSP00000441229 ENST00000536101	A0A075B6F5 [Direct mapping] Unconventional myosin-XVIIIb Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003774 [motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0008152 [metabolic process] GO:0016459 [myosin complex] Show all	2567 aa 285.2 kDa	No	0
MYO18B-006 ENSP00000386096 ENST00000407587	F5GXR6 [Direct mapping] Unconventional myosin-XVIIIb Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003774 [motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0008152 [metabolic process] GO:0016459 [myosin complex] Show all	2568 aa 285.3 kDa	No	0
MYO18B-007 ENSP00000444262 ENST00000543971	H0YGQ4 [Direct mapping] Unconventional myosin-XVIIIb Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		517 aa 56.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.