Tissue expression of BTG1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	BTG1
Gene description	B-cell translocation gene 1, anti-proliferative
Protein class	Cancer-related genes Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	BTG1
Synonyms
Description	B-cell translocation gene 1, anti-proliferative (HGNC Symbol)
Entrez gene summary	This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
Chromosome	12
Cytoband	q21.33
Chromosome location (bp)	92140278 - 92145897
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133639 (version 83.38)
Entrez gene	694
UniProt	P62324 (UniProt - Evidence at protein level)
neXtProt	NX_P62324
Antibodypedia	BTG1 antibodies

PROTEIN BROWSER

BTG1-001	BTG1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTG1-001 ENSP00000256015 ENST00000256015	P62324 [Direct mapping] Protein BTG1 Q6IBC8 [Target identity:100%; Query identity:100%] B-cell translocation gene 1, anti-proliferative; B-cell translocation gene 1, anti-proliferative, isoform CRA_b; BTG1; BTG1 protein; cDNA, FLJ93822, Homo sapiens B-cell translocation gene 1, anti-proliferative(BTG1), mRNA Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0003712 [transcription cofactor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006479 [protein methylation] GO:0006979 [response to oxidative stress] GO:0007283 [spermatogenesis] GO:0008285 [negative regulation of cell proliferation] GO:0016477 [cell migration] GO:0019899 [enzyme binding] GO:0019900 [kinase binding] GO:0030308 [negative regulation of cell growth] GO:0043434 [response to peptide hormone] GO:0045603 [positive regulation of endothelial cell differentiation] GO:0045663 [positive regulation of myoblast differentiation] GO:0045766 [positive regulation of angiogenesis] GO:2000271 [positive regulation of fibroblast apoptotic process] Show all	171 aa 19.2 kDa	No	0
BTG1-003 ENSP00000447551 ENST00000552315	F8W0U7 [Direct mapping] Protein BTG1 Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		84 aa 9.2 kDa	No	0