Tissue expression of DYDC2 - Summary - The Human Protein Atlas

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DYDC2

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DYDC2
Gene description	DPY30 domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (fallopian tube)
GTEx:	Tissue enhanced (fallopian tube, testis)
FANTOM5:	Group enriched (caudate, epididymis, hippocampus, lung, ovary, testis)

Protein evidence

Evidence at protein level

Protein expression

Selective expression in ciliated cells of respiratory epithelia, fallopian tube and a subset of cells in endometrium.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA038006 , HPA038007
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (fallopian tube)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (fallopian tube, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, epididymis, hippocampus, lung, ovary, testis)

GENE INFORMATION
Gene name	DYDC2 (HGNC Symbol)
Synonyms	bA36D19.6, MGC16186
Description	DPY30 domain containing 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins that contains a DPY30 domain. This gene locus overlaps with a closely related gene on the opposite strand. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Chromosome	10
Cytoband	q23.1
Chromosome location (bp)	80344745 - 80368073
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133665 (version 83.38)
Entrez gene	84332
UniProt	Q96IM9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96IM9
Antibodypedia	DYDC2 antibodies

PROTEIN BROWSER

DYDC2-001	DYDC2-002	DYDC2-003	DYDC2-004	DYDC2-005	DYDC2-201	DYDC2-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DYDC2-001 ENSP00000361273 ENST00000372199	Q96IM9 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.6 kDa	No	0
DYDC2-002 ENSP00000361271 ENST00000372197	Q96IM9 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.6 kDa	No	0
DYDC2-003 ENSP00000256039 ENST00000256039	Q96IM9 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.6 kDa	No	0
DYDC2-004 ENSP00000401333 ENST00000411538	X1WI30 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	126 aa 14.9 kDa	No	0
DYDC2-005 ENSP00000361272 ENST00000372198	A0A0A0MRQ7 [Direct mapping] DPY30 domain-containing protein 2; Uncharacterized protein Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	191 aa 22.1 kDa	No	0
DYDC2-201 ENSP00000410285 ENST00000444807	Q96IM9 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.6 kDa	No	0
DYDC2-202 ENSP00000483479 ENST00000616870	Q96IM9 [Direct mapping] DPY30 domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0006348 [chromatin silencing at telomere] GO:0042800 [histone methyltransferase activity (H3-K4 specific)] GO:0048188 [Set1C/COMPASS complex] GO:0051568 [histone H3-K4 methylation] Show all	177 aa 20.6 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.