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ADAMDEC1

GENERAL INFORMATION

Gene name

 ADAMDEC1

Gene description

 ADAM-like, decysin 1

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Group enriched (U-266/70, U-266/84)
HPA (normal tissue):Tissue enhanced (colon, rectum, small intestine)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 ADAMDEC1 (HGNC Symbol)

Synonyms

 M12.219

Description

 ADAM-like, decysin 1 (HGNC Symbol)

Entrez gene summary

 This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 p21.2

Chromosome location (bp)

 24384285 - 24406013

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000134028 (version 83.38)

Entrez gene

 27299

UniProt

 O15204 (UniProt - Evidence at protein level)

neXtProt

 NX_O15204

Antibodypedia

 ADAMDEC1 antibodies

PROTEIN BROWSER
ADAMDEC1-001
ADAMDEC1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ADAMDEC1-001
ENSP00000256412
ENST00000256412
O15204 [Direct mapping]
ADAM DEC1
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Enzymes
   Peptidases
   Metallopeptidases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004222 [metalloendopeptidase activity]
GO:0005575 [cellular_component]
GO:0005576 [extracellular region]
GO:0006508 [proteolysis]
GO:0006955 [immune response]
GO:0007162 [negative regulation of cell adhesion]
GO:0008270 [zinc ion binding]
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 470 aa
52.8 kDa 		Yes 0
ADAMDEC1-002
ENSP00000428993
ENST00000522298
O15204 [Direct mapping]
ADAM DEC1
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Enzymes
   Peptidases
   Metallopeptidases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004222 [metalloendopeptidase activity]
GO:0005575 [cellular_component]
GO:0005576 [extracellular region]
GO:0006508 [proteolysis]
GO:0006955 [immune response]
GO:0007162 [negative regulation of cell adhesion]
GO:0008270 [zinc ion binding]
Show all
 391 aa
43.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.