Tissue expression of ADAMDEC1 - Summary

GENERAL INFORMATION
Gene name	ADAMDEC1
Gene description	ADAM-like, decysin 1
Protein class	Enzymes Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (colon, rectum, small intestine)
GTEx:	Group enriched (colon, small intestine)
FANTOM5:	Tissue enhanced (appendix, colon, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, rectum, small intestine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (appendix, colon, small intestine)

GENE INFORMATION
Gene name	ADAMDEC1 (HGNC Symbol)
Synonyms	M12.219
Description	ADAM-like, decysin 1 (HGNC Symbol)
Entrez gene summary	This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	p21.2
Chromosome location (bp)	24384285 - 24406013
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134028 (version 83.38)
Entrez gene	27299
UniProt	O15204 (UniProt - Evidence at protein level)
neXtProt	NX_O15204
Antibodypedia	ADAMDEC1 antibodies

PROTEIN BROWSER

ADAMDEC1-001	ADAMDEC1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADAMDEC1-001 ENSP00000256412 ENST00000256412	O15204 [Direct mapping] ADAM DEC1 Show all	Enzymes Peptidases Metallopeptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0006508 [proteolysis] GO:0006955 [immune response] GO:0007162 [negative regulation of cell adhesion] GO:0008270 [zinc ion binding] Show all	470 aa 52.8 kDa	Yes	0
ADAMDEC1-002 ENSP00000428993 ENST00000522298	O15204 [Direct mapping] ADAM DEC1 Show all	Enzymes Peptidases Metallopeptidases THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0006508 [proteolysis] GO:0006955 [immune response] GO:0007162 [negative regulation of cell adhesion] GO:0008270 [zinc ion binding] Show all	391 aa 43.6 kDa	No	0