Expression of PRPF38B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PRPF38B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRPF38B
Gene description	Pre-mRNA processing factor 38B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in subset of immune cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Antibody staining in cells/structures not annotated, view images.
Reliability score	Approved based on 1 antibody. HPA053255
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA053255

GENE INFORMATION
Gene name	PRPF38B (HGNC Symbol)
Synonyms	FLJ10330, NET1
Description	Pre-mRNA processing factor 38B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	108692323 - 108701803
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134186 (version 83.38)
Entrez gene	55119
UniProt	Q5VTL8 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VTL8
Antibodypedia	PRPF38B antibodies

PROTEIN BROWSER

PRPF38B-001	PRPF38B-002	PRPF38B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRPF38B-001 ENSP00000359042 ENST00000370025	Q5VTL8 [Direct mapping] Pre-mRNA-splicing factor 38B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0044822 [poly(A) RNA binding] GO:0071011 [precatalytic spliceosome] Show all	546 aa 64.5 kDa	No	0
PRPF38B-002 ENSP00000359038 ENST00000370021	A0A0A0MRN0 [Direct mapping] PRP38 pre-mRNA processing factor 38 (Yeast) domain containing B, isoform CRA_b; Pre-mRNA-splicing factor 38B Show all	TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0071011 [precatalytic spliceosome] Show all	435 aa 52.5 kDa	No	0
PRPF38B-004 ENSP00000359039 ENST00000370022	Q5VTL8 [Direct mapping] Pre-mRNA-splicing factor 38B Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0044822 [poly(A) RNA binding] GO:0071011 [precatalytic spliceosome] Show all	190 aa 21.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.