Cell atlas - NAPG - The Human Protein Atlas

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NAPG

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	NAPG
Gene description	N-ethylmaleimide-sensitive factor attachment protein, gamma
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA008208
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane & cytosol.

Main location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA008208	A-431	Cytosol
	HPA008208	U-2 OS	Plasma membrane
	HPA008208	U-2 OS	Cytosol

GENE INFORMATION
Gene name	NAPG
Synonyms
Description	N-ethylmaleimide-sensitive factor attachment protein, gamma (HGNC Symbol)
Entrez gene summary	This gene encodes soluble NSF attachment protein gamma. The soluble NSF attachment proteins (SNAPs) enable N-ethyl-maleimide-sensitive fusion protein (NSF) to bind to target membranes. NSF and SNAPs appear to be general components of the intracellular membrane fusion apparatus, and their action at specific sites of fusion must be controlled by SNAP receptors particular to the membranes being fused. The product of this gene mediates platelet exocytosis and controls the membrane fusion events of this process.[provided by RefSeq, Dec 2008]
Chromosome	18
Cytoband	p11.22
Chromosome location (bp)	10525905 - 10552761
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134265 (version 83.38)
Entrez gene	8774
UniProt	Q99747 (UniProt - Evidence at protein level)
neXtProt	NX_Q99747
Antibodypedia	NAPG antibodies

PROTEIN BROWSER

NAPG-001	NAPG-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAPG-001 ENSP00000324628 ENST00000322897	Q99747 [Direct mapping] Gamma-soluble NSF attachment protein Q6FHY4 [Target identity:100%; Query identity:100%] N-ethylmaleimide-sensitive factor attachment protein, gamma, isoform CRA_b; NAPG protein; cDNA, FLJ95310, Homo sapiens N-ethylmaleimide-sensitive factor attachment protein,gamma (NAPG), mRNA Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005483 [soluble NSF attachment protein activity] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005765 [lysosomal membrane] GO:0006461 [protein complex assembly] GO:0006886 [intracellular protein transport] GO:0006891 [intra-Golgi vesicle-mediated transport] GO:0019905 [syntaxin binding] GO:0031201 [SNARE complex] GO:0043209 [myelin sheath] GO:0050821 [protein stabilization] GO:0061025 [membrane fusion] GO:0070062 [extracellular exosome] Show all	312 aa 34.7 kDa	No	0
NAPG-006 ENSP00000463018 ENST00000582472	J3KTJ6 [Direct mapping] Gamma-soluble NSF attachment protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005483 [soluble NSF attachment protein activity] GO:0006886 [intracellular protein transport] GO:0019905 [syntaxin binding] GO:0031201 [SNARE complex] Show all	177 aa 19.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.