Cell atlas - ECHDC3 - The Human Protein Atlas

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ECHDC3

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria
	Nucleoli
	Nucleus

Human cell
	Mitochondria
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ECHDC3
Gene description	Enoyl CoA hydratase domain containing 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus & nucleoli. In addition localized to the mitochondria.
RNA cell category	Cell line enhanced (A-431, BEWO)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved), Nucleoli (approved)
Additional location	In addition localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA038306
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (A-431, BEWO) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus & nucleoli. In addition localized to the mitochondria.

Main location

Nucleus (approved), Nucleoli (approved)

Additional location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA038306	A-431	Nucleus
			Nucleoli
			Mitochondria
	HPA038306	U-2 OS	Nucleoli
	HPA038306	U-251 MG	Nucleus
			Nucleoli
			Vesicles

GENE INFORMATION
Gene name	ECHDC3 (HGNC Symbol)
Synonyms	FLJ20909
Description	Enoyl CoA hydratase domain containing 3 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p14
Chromosome location (bp)	11742366 - 11764070
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134463 (version 83.38)
Entrez gene	79746
UniProt	Q96DC8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DC8
Antibodypedia	ECHDC3 antibodies

PROTEIN BROWSER

ECHDC3-001	ECHDC3-004	ECHDC3-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ECHDC3-001 ENSP00000368517 ENST00000379215	Q96DC8 [Direct mapping] Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005739 [mitochondrion] GO:0008152 [metabolic process] Show all	303 aa 32.6 kDa	No	0
ECHDC3-004 ENSP00000405584 ENST00000420401	Q5W0J8 [Direct mapping] Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	241 aa 25.4 kDa	No	0
ECHDC3-005 ENSP00000398429 ENST00000422887	Q5W0J6 [Direct mapping] Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	166 aa 17.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.